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Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.

1 Sept 1990

Abstract excerpt

Human mammary cells present on the cell surface a polymorphic epithelial mucin (PEM) which is developmentally regulated and aberrantly expressed in tumors. PEM carries tumor-associated epitopes recognized by the monoclonal antibodies HMFG-1, HMFG-2, and SM-3. Previously isolated partial cDNA clones revealed that the core protein contained a large domain consisting of variable numbers of 20-amino acid repeat...

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PMID: 1697589
DOI: 10.1016/s0021-9258(18)77254-2

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