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Identification of proacrosin binding protein sp32 precursor as a human cancer/testis antigen

13 Mar 2001

Abstract excerpt

Serological expression cloning of antigens eliciting a humoral immune response to a syngeneic mouse sarcoma identified pem (mouse placenta and embryonic expression gene) as a new member of the cancer/testis family. To identify the human homologue of pem, mouse pem sequences and pem-related expressed sequence tags from human testis were used as PCR primers for amplification using human testis cDNA. However, rather...

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PMID: 11248070
DOI: 10.1073/pnas.041625098

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