Heteroduplex analysis of T-cell receptor gamma gene rearrangements for diagnosis and monitoring of cutaneous T-cell lymphomas

Abstract excerpt

The possibility to detect markers of T-cell clonality at the T-cell receptor (TCR) beta and gamma loci in skin biopsy samples has proven to be helpful for the often difficult clinical and immunohistochemical diagnosis of cutaneous T-cell lymphoma (CTCL). However, particularly at the early stage of the neoplastic infiltration, an emerging clonal pattern at Southern may be obscured by the germline TCR configuration...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cutaneous lymphoproliferative disorders research
• Share to Fungal Infections and Studies
• Share to Lymphoma Diagnosis and Treatment