Increased thrombosis incidence in a family with an inherited protein S deficiency and a high oxygen affinity hemoglobin variant.

doi:10.1002/ajh.2830460310

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Article

Increased thrombosis incidence in a family with an inherited protein S deficiency and a high oxygen affinity hemoglobin variant.

American journal of hematology - 1 Jul 1994

Berruyer M, Francina A, Ffrench P, Negrier C, Boneu B, Dechavanne M

Abstract excerpt

Inherited protein S deficiency and the presence of a rare high oxygen affinity hemoglobin variant: Hb Rainier [beta 145 (HC2) Tyr-->Cys] were found in a family. Among 16 studied members, nine were found as carriers of protein S deficiency (type I with decrease of total, free, and activity levels)...

Topics

Adult
Aged
Aged, 80 and over
Family Health
Female
Genetic Variation
Hemoglobins, Abnormal
Humans
Incidence
Male
Middle Aged
Pedigree
Protein S Deficiency
Thrombophlebitis

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