Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepadnavirus reverse transcription initiates within the stem-loop of the RNA packaging signal and employs a novel strand transfer.

Journal of virology - 1 Jun 1994

Tavis J E, Perri S, Ganem D

Abstract excerpt

Replication of the hepadnavirus genome occurs by reverse transcription of an RNA pregenome and is mediated by the viral polymerase; the polymerase is also required for packaging of the pregenome through interaction with the RNA packaging signal, epsilon. Previous work suggested that reverse transcription of minus-strand DNA initiates within the sequence element DR1 (direct repeat 1) and that disruption of DR1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Primers
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression

Share to Molecular Sequence Data

Share to Mutation

Share to Saccharomyces cerevisiae

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 8189492
DOI: 10.1128/JVI.68.6.3536-3543.1994
PMCID: PMC236857

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepadnavirus reverse transcription initiates within the stem-loop of the RNA packaging signal and employs a novel strand transfer.PMID 8189492Read ↗

RNA sequences controlling the initiation and transfer of duck hepatitis B virus minus-strand DNA.Semantic proximity Read ↗

Specific hepatitis B virus minus-strand DNA synthesis requires only the 5' encapsidation signal and the 3'-proximal direct repeat DR1Semantic proximity Read ↗

A short cis-acting sequence is required for hepatitis B virus pregenome encapsidation and sufficient for packaging of foreign RNA.Semantic proximity Read ↗

Circularization of an RNA template via long-range base pairing is critical for hepadnaviral reverse transcription.Semantic proximity Read ↗

A pregenomic RNA sequence adjacent to DR1 and complementary to epsilon influences hepatitis B virus replication efficiency.Semantic proximity Read ↗

A bulged region of the hepatitis B virus RNA encapsidation signal contains the replication origin for discontinuous first-strand DNA synthesisSemantic proximity Read ↗

Mutations in the epsilon sequences of human hepatitis B virus affect both RNA encapsidation and reverse transcription.Semantic proximity Read ↗

Structure and function of the encapsidation signal of hepadnaviridae.Semantic proximity Read ↗

Sequence- and structure-specific determinants in the interaction between the RNA encapsidation signal and reverse transcriptase of avian hepatitis B viruses.Semantic proximity Read ↗

Base Pairing between the 5′ Half of ε and a <i>cis</i> -Acting Sequence, Φ, Makes a Contribution to the Synthesis of Minus-Strand DNA for Human Hepatitis B VirusSemantic proximity Read ↗

Hepatitis B virus replicationSemantic proximity Read ↗

A yeast-based reverse genetics system to generate HCoV-OC43 reporter viruses encoding an eighth sgRNASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.