Effect of alterations of basic amino acid residues of Escherichia coli heat-stable enterotoxin II on enterotoxicity.

doi:10.1128/iai.62.6.2295-2301.1994

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Article

Effect of alterations of basic amino acid residues of Escherichia coli heat-stable enterotoxin II on enterotoxicity.

Infection and immunity - 1 Jun 1994

Fujii Y, Okamuro Y, Hitotsubashi S, Saito A, Akashi N, Okamoto K

Abstract excerpt

Escherichia coli heat-stable enterotoxin II (STII) is composed of 48 amino acid residues. Among these, one histidine, two arginine, and six lysine residues are basic. Isoelectric focusing showed that the isoelectric point of STII is 9.7, indicating that the side chains of some of these basic amin...

Topics

Animals
Bacterial Toxins
Base Sequence
Enterotoxins
Escherichia coli
Escherichia coli Proteins
Intestines
Isoelectric Point
Mice
Molecular Sequence Data
Mutation
Structure-Activity Relationship

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