Article
Amino-acid residues involved in biological functions of the cytolytic enterotoxin from Aeromonas hydrophila.
Gene - 14 Apr 1995
Ferguson M R, Xu X J, Houston C W, Peterson J W, Chopra A K
Abstract excerpt
Some amino acid (aa) residues within the cytolytic enterotoxin (Act) of Aeromonas hydrophila essential for biological activity were identified. Act is a 52-kDa polypeptide, possessing hemolytic, cytotoxic and enterotoxic activities. By deletion analysis, generation of anti-peptide Ab, and site-di...
Topics
- Aeromonas hydrophila
- Amino Acid Sequence
- Amino Acids
- Animals
- Bacterial Toxins
- Binding, Competitive
- CHO Cells
- Cells, Cultured
- Cricetinae
- Cytotoxins
- Enterotoxins
- Epitopes
- Erythrocytes
- Ileum
- Molecular Sequence Data
- Mutation
- Neutralization Tests
- Peptide Fragments