Article
Allelic stability of VNTR locus 3' alpha HVR: linkage disequilibrium with the common alpha-thalassaemia-1 deletion of South-East Asia (--SEA/).
Human heredity - 1 Jan 2000
Waye J S, Eng B
Abstract excerpt
Variable number of tandem repeats (VNTR) loci are among the most polymorphic sequences described to date. VNTR allelic variability is a function of the high rates of de novo mutation due to intra- and inter-allelic recombination. We have assessed the allelic stability of VNTRs during recent human...
Topics
- Alleles
- Asia, Southeastern
- Biological Evolution
- Globins
- Humans
- Linkage Disequilibrium
- Multigene Family
- Repetitive Sequences, Nucleic Acid
- Sequence Deletion
- alpha-Thalassemia
