Article
Intra- and intercontinental molecular variability of an Alu insertion in the 3' untranslated region of the LDLR gene.
Human biology - 1 Aug 2004
Heller A H, Salzano F M, Barrantes R, Krylov M, Benevolenskaya L, Arnett F C, Munkhbat B, Munkhtuvshin N, Tsuji K, Hutz M H, Carnese F R, Goicoechea A S, Freitas L B, Bonatto S L
Abstract excerpt
One-hundred three individuals from two Mongolian, two Siberian, and ten native American populations were studied in relation to a 340-bp sequence from an Alu insertion located in the 3' untranslated region of the LDLR gene. Seven haplotypes have been determined, and haplotype B1 was the most common, accounting for about half the sequences found. In general, diversity values are quite high, about 2.5 times higher...
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