VNTR alleles associated with the alpha-globin locus are haplotype and population related.

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Article

VNTR alleles associated with the alpha-globin locus are haplotype and population related.

American journal of human genetics - 1 Sept 1994

Martinson J J, Boyce A J, Clegg J B

Abstract excerpt

The human alpha-globin complex contains several polymorphic restriction-enzyme sites (i.e., RFLPs) linked to form haplotypes and is flanked by two hypervariable VNTR loci, the 5' hypervariable region (HVR) and the more highly polymorphic 3'HVR. Using a combination of RFLP analysis and PCR, we hav...

Topics

Alleles
Base Sequence
Chromosome Deletion
Chromosomes, Human, Pair 16
Consensus Sequence
DNA Primers
Genetic Variation
Globins
Haplotypes
Humans
Melanesia
Molecular Sequence Data
Phylogeny
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Polynesia
Repetitive Sequences, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 7915879
PMCID: PMC1918386

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7915879-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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