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Article

Ligand-dependent stimulation of introduced mammalian brain receptors alters spicule symmetry and other morphogenetic events in sea urchin embryos.

Mechanisms of development - 1 Jan 1994

Cameron R A, Smith L C, Britten R J, Davidson E H

Abstract excerpt

Zygotes of S. purpuratus were injected with synthetic mRNAs encoding rodent brain neurotransmitter receptors, and specific developmental phenotypes were produced on addition to the sea water of the respective ligands. Most of these experiments were carried out with a mouse serotonin receptor (5HT...

Topics

Animals
Blastocyst
Brain
Brain Chemistry
Ectoderm
Fluorescent Antibody Technique
Gastrula
In Situ Hybridization
Ligands
Microinjections
Morphogenesis
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Messenger

Receptors, Cholinergic

Receptors, Serotonin

Sea Urchins

Signal Transduction

Source

Identifiers

PMID: 8186147
DOI: 10.1016/0925-4773(94)90051-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8186147-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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