Knockdown of spalt function by RNAi causes de-repression of Hox genes and homeotic transformations in the crustacean Artemia franciscana.

doi:10.1016/j.ydbio.2006.07.024

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Article

Knockdown of spalt function by RNAi causes de-repression of Hox genes and homeotic transformations in the crustacean Artemia franciscana.

Developmental biology - 1 Oct 2006

Copf Tijana, Rabet Nicolas, Averof Michalis

Abstract excerpt

Hox genes play a central role in the specification of distinct segmental identities in the body of arthropods. The specificity of Hox genes depends on their restricted expression domains, their interaction with specific cofactors and selectivity for particular target genes. spalt genes are associated with the function of Hox genes in diverse species, but the nature of this association varies: in some cases, spalt...

Topics

Animals
Artemia
Body Patterning
Drosophila Proteins
Embryo, Nonmammalian
Gene Expression Regulation, Developmental
Genes, Homeobox
Genitalia
Homeodomain Proteins
Phenotype
RNA Interference
Thorax
Transcription Factors
Transformation, Genetic

Source

Open in PubMed

Identifiers

PMID: 16934794
DOI: 10.1016/j.ydbio.2006.07.024

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