Article
Protease-dependent T cell activation: ligation of effector cell protease receptor-1 (EPR-1) stimulates lymphocyte proliferation.
Cellular immunology - 1 May 1994
Altieri D C, Stamnes S J
Abstract excerpt
Blood proteases regulate cellular growth through the recognition and signaling properties of specialized membrane receptors. Previous studies have identified a novel lymphocyte activation-dependent antigen, denominated effector cell protease receptor-1 (EPR-1), which binds the coagulation protease factor Xa on various leukocyte subsets. Here we show that occupancy of EPR-1 with physiologic concentrations of...
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