Protease-dependent T cell activation: ligation of effector cell protease receptor-1 (EPR-1) stimulates lymphocyte proliferation.

doi:10.1006/cimm.1994.1130

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Article

Protease-dependent T cell activation: ligation of effector cell protease receptor-1 (EPR-1) stimulates lymphocyte proliferation.

Cellular immunology - 1 May 1994

Altieri D C, Stamnes S J

Abstract excerpt

Blood proteases regulate cellular growth through the recognition and signaling properties of specialized membrane receptors. Previous studies have identified a novel lymphocyte activation-dependent antigen, denominated effector cell protease receptor-1 (EPR-1), which binds the coagulation proteas...

Topics

Antibodies, Monoclonal
Calcium
Cells, Cultured
Cross-Linking Reagents
Cytosol
Dose-Response Relationship, Drug
Factor Xa
Flow Cytometry
Humans
Inhibitor of Apoptosis Proteins
Interleukin-2
Lymphocyte Activation
Phenotype
Receptors, Cell Surface
Serine Endopeptidases
Signal Transduction
Survivin
T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 8181072
DOI: 10.1006/cimm.1994.1130

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8181072-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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