Article
Increases in cell size at START caused by hyperactivation of the cAMP pathway in Saccharomyces cerevisiae.
Molecular & general genetics : MGG - 1 Apr 1994
Mitsuzawa H
Abstract excerpt
In the budding yeast Saccharomyces cerevisiae, passage through START, which commits cells to a new round of cell division, requires growth to a critical size. To examine the effect of hyperactivation of the cAMP pathway on cell size at START, a strain was constructed that is able to respond to exogenously added cAMP. In the presence of cAMP, this strain showed increased cell volume at bud emergence, suggesting...
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