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Article

Increases in cell size at START caused by hyperactivation of the cAMP pathway in Saccharomyces cerevisiae.

Molecular & general genetics : MGG - 1 Apr 1994

Mitsuzawa H

Abstract excerpt

In the budding yeast Saccharomyces cerevisiae, passage through START, which commits cells to a new round of cell division, requires growth to a critical size. To examine the effect of hyperactivation of the cAMP pathway on cell size at START, a strain was constructed that is able to respond to exogenously added cAMP. In the presence of cAMP, this strain showed increased cell volume at bud emergence, suggesting...

Topics

Alleles
CDC28 Protein Kinase, S cerevisiae
Cell Cycle
Cell Size
Culture Media
Cyclic AMP
Cyclic AMP-Dependent Protein Kinases
Cyclins
Enzyme Activation
Fungal Proteins
G1 Phase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression Regulation, Fungal

Genes, Fungal

Genes, Switch

Saccharomyces cerevisiae

Source

Identifiers

PMID: 8177212
DOI: 10.1007/BF00280312

Genes

CLN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8177212-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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