Article
Cerebellar beta 2-chimaerin, a GTPase-activating protein for p21 ras-related rac is specifically expressed in granule cells and has a unique N-terminal SH2 domain.
The Journal of biological chemistry - 29 Apr 1994
Leung T, How B E, Manser E, Lim L
Abstract excerpt
beta-Chimaerin, a 30-kDa GTPase-activating protein (GAP) for the p21 Ras-related Rac, is expressed specifically in late stage spermatocytes (Leung, T., How, B.-E., Manser, E., and Lim, L. (1993) J. Biol. Chem. 268, 3813-3816). Using antibodies raised against beta-chimaerin, we detected a major 46...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cerebellum
- DNA, Complementary
- GTP-Binding Proteins
- GTPase-Activating Proteins
- Humans
- Molecular Sequence Data
- Mutation
- Neoplasm Proteins
- Proteins
- Rats
- Rats, Sprague-Dawley
- Sequence Alignment
- Synaptosomes
- rac GTP-Binding Proteins
- ras GTPase-Activating Proteins