Article
Localization of the protein 4.1-binding site on human erythrocyte glycophorins C and D.
The Biochemical journal - 1 Apr 1994
Hemming N J, Anstee D J, Mawby W J, Reid M E, Tanner M J
Abstract excerpt
The flexibility of the human erythrocyte membrane is mediated by an underlying network of skeletal proteins which interact with the membrane through ankyrin and protein 4.1. The nature of the membrane attachment site(s) for protein 4.1 has yet to be fully elucidated. In this paper we show that purified protein 4.1 binds much less strongly to alkali-stripped membranes from erythrocytes of individuals with total...
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