The origin of the primate Mhc-DRB genes and allelic lineages as deduced from the study of prosimians.

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Article

The origin of the primate Mhc-DRB genes and allelic lineages as deduced from the study of prosimians.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 1994

Figueroa F, O'hUigin C, Tichy H, Klein J

Abstract excerpt

MHC class II genes of the DRB family were partially sequenced from 10 individuals representing six species of prosimians: Galago senegalensis, G. moholi, Otolemur garnetti, Loris tardigradus, Petterus (Lemur) fulvus, and Lemur catta. Altogether, 41 different genes were discerned, all distinct from genes identified previously. Comparative analysis of the sequences has led to the following conclusions. First, the...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Biological Evolution
Consensus Sequence
DNA Primers
DNA, Complementary
Genes, MHC Class II
HLA-DR Antigens
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Multigene Family

Phylogeny

Primates

Pseudogenes

Sequence Homology, Amino Acid

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 8157963

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8157963-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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