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Article

Dynamic behavior of hepatitis C virus quasispecies in patients undergoing orthotopic liver transplantation.

Journal of virology - 1 May 1994

Martell M, Esteban J I, Quer J, Vargas V, Esteban R, Guardia J, Gómez J

Abstract excerpt

We have studied the distribution of viral sequences from the 5' noncoding region and from a fragment of the E2/NS2 region of the hepatitis C virus (HCV) genome in samples obtained before and after liver transplantation in two patients with HCV cirrhosis. The population of viral sequences in both regions were established by sequencing cloned PCR products. In both cases, the complexity of the viral quasispecies...

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Identifiers

PMID: 8151804
DOI: 10.1128/JVI.68.5.3425-3436.1994
PMCID: PMC236838

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