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Article

The UL21 gene products of herpes simplex virus 1 are dispensable for growth in cultured cells.

Journal of virology - 1 May 1994

Baines J D, Koyama A H, Huang T, Roizman B

Abstract excerpt

A viral deletion mutant (delta UL21) that lacked the sequences encoding 484 of the predicted first 535 amino acids of the UL21 open reading frame was genetically engineered and studied with respect to its phenotype in cells in culture. We report the following. (i) The replication of delta UL21 was identical to that of the parent herpes simplex virus 1 (HSV-1) strain F in Vero cells, but the yields were three- to...

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Identifiers

PMID: 8151763
DOI: 10.1128/JVI.68.5.2929-2936.1994
PMCID: PMC236781

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The UL21 gene products of herpes simplex virus 1 are dispensable for growth in cultured cells.PMID 8151763Read ↗

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Human Cytomegalovirus Early Protein pUL21a Promotes Efficient Viral DNA Synthesis and the Late Accumulation of Immediate-Early TranscriptsSemantic proximity Read ↗

Identification of three genes nonessential for growth in cell culture near the right terminus of the unique sequences of long component of herpes simplex virus 1.Semantic proximity Read ↗

Functional Domains of the Herpes Simplex Virus Type 1 Tegument Protein pUL37: The Amino Terminus is Dispensable for Virus Replication in Tissue Culture.Semantic proximity Read ↗

The open reading frames UL3, UL4, UL10, and UL16 are dispensable for the replication of herpes simplex virus 1 in cell culture.Semantic proximity Read ↗

In vitro characterization of the HSV-1 UL53 gene productSemantic proximity Read ↗

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Herpes simplex virus encodes a virion-associated protein which promotes long cellular processes in over-expressing cells.Semantic proximity Read ↗

Investigating the structure and function of HSV-1 tegument proteins, UL7 and UL51Semantic proximity Read ↗

Characterization of the protein encoded by gene UL49A of herpes simplex virus type 1.Semantic proximity Read ↗

Site-directed mutagenesis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): analysis of functional differences between HSV type 1 (HSV-1) and HSV-2 alleles.Semantic proximity Read ↗

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