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Article

The UL21 Tegument Protein of Herpes Simplex Virus 1 Is Differentially Required for the Syncytial Phenotype.

Journal of virology - 1 Nov 2017

Sarfo Akua, Starkey Jason, Mellinger Erica, Zhang Dan, Chadha Pooja, Carmichael Jillian, Wills John W

Abstract excerpt

The initial goal of this study was to reexamine the requirement of UL21 for herpes simplex virus 1 (HSV-1) replication. Previous studies suggested that UL21 is dispensable for replication in cell cultures, but a recent report on HSV-2 challenges those findings. As was done for the HSV-2 study, a UL21-null virus was made and propagated on complementing cells to discourage selection of compensating mutations. This...

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Source

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Identifiers

PMID: 28794039
DOI: 10.1128/JVI.01161-17
PMCID: PMC5640837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The UL21 Tegument Protein of Herpes Simplex Virus 1 Is Differentially Required for the Syncytial Phenotype.PMID 28794039Read ↗

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