A pleiotropic phospholipid biosynthetic regulatory mutation in Saccharomyces cerevisiae is allelic to sin3 (sdi1, ume4, rpd1).

doi:10.1093/genetics/136.2.475

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

A pleiotropic phospholipid biosynthetic regulatory mutation in Saccharomyces cerevisiae is allelic to sin3 (sdi1, ume4, rpd1).

Genetics - 1 Feb 1994

Hudak K A, Lopes J M, Henry S A

Abstract excerpt

Three mutants were identified in a genetic screen using an INO1-lacZ fusion to detect altered INO1 regulation in Saccharomyces cerevisiae. These strains harbor mutations that render the cell unable to fully repress expression of INO1, the structural gene for inositol-1-phosphate synthase. The Cpe...

Topics

Alleles
Choline
Chromosome Mapping
Enzyme Induction
Epistasis, Genetic
Fungal Proteins
Gene Expression Regulation, Fungal
Genes, Fungal
Genes, Regulator
Genetic Complementation Test
Histone Deacetylases
Inositol
Mutation
Myo-Inositol-1-Phosphate Synthase
Phenotype
Phospholipids
Recombinant Fusion Proteins
Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 8150277
DOI: 10.1093/genetics/136.2.475
PMCID: PMC1205802

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8150277-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics