Article
A pleiotropic phospholipid biosynthetic regulatory mutation in Saccharomyces cerevisiae is allelic to sin3 (sdi1, ume4, rpd1).
Genetics - 1 Feb 1994
Hudak K A, Lopes J M, Henry S A
Abstract excerpt
Three mutants were identified in a genetic screen using an INO1-lacZ fusion to detect altered INO1 regulation in Saccharomyces cerevisiae. These strains harbor mutations that render the cell unable to fully repress expression of INO1, the structural gene for inositol-1-phosphate synthase. The Cpe-(constitutive phospholipid gene expression) phenotype associated with these mutations segregated 2:2, indicating that...
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