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Article

A dominant mutation that alters the regulation of INO1 expression in Saccharomyces cerevisiae.

Journal of biochemistry - 1 Mar 1992

Hosaka K, Nikawa J, Kodaki T, Yamashita S

Abstract excerpt

A dominant, single nuclear gene mutation, CSE1, caused inositol auxotrophy in yeast cells. The inositol requirement was marked when choline was present in the medium. Inositol-1-phosphate synthase, the regulatory enzyme of inositol synthesis, is repressed by inositol, or more profoundly by a comb...

Topics

Carbon Radioisotopes
Choline
Escherichia coli
Genes, Dominant
Genes, Fungal
Methionine
Mutation
Myo-Inositol-1-Phosphate Synthase
Saccharomyces cerevisiae

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1587797
DOI: 10.1093/oxfordjournals.jbchem.a123761

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1587797-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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A dominant mutation that alters the regulation of INO1 expression in Saccharomyces cerevisiae.PMID 1587797Read ↗

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The role of phosphatidylcholine biosynthesis in the regulation of the INO1 gene of yeast.Semantic proximity Read ↗

Genome expression analysis in yeast reveals novel transcriptional regulation by inositol and choline and new regulatory functions for Opi1p, Ino2p, and Ino4p.Semantic proximity Read ↗

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