Article
The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells.
Molecular and cellular biology - 1 Apr 1994
Selvakumaran M, Lin H K, Sjin R T, Reed J C, Liebermann D A, Hoffman B
Abstract excerpt
Cell numbers are regulated by a balance among proliferation, growth arrest, and programmed cell death. A profound example of cell homeostasis, controlled throughout life, is the complex process of blood cell development, yet little is understood about the intracellular mechanisms that regulate bl...
Topics
- Animals
- Antigens, Differentiation
- Apoptosis
- Cell Division
- Cell Line
- Clone Cells
- Gene Expression Regulation, Neoplastic
- Genes, myc
- Genetic Variation
- Kinetics
- Leukemia, Experimental
- Leukemia, Myeloid
- Mice
- Polymerase Chain Reaction