Article
The open reading frames 1, 2, 71, and 75 are nonessential for the replication of equine herpesvirus type 1 in vitro.
Virology - 1 Mar 1994
Sun Y, Brown S M
Abstract excerpt
Equine herpesvirus type 1 (EHV-1) strain Ab4 has five genes, 1, 2, 67, 71, and 75, which have no homologues in any of the herpesviruses sequenced to date; i.e., they are unique to EHV-1. The functions of these unique genes are not known. To study their role in the virus life cycle, we have constructed four independent mutants in which the majority of the coding sequences of genes 1, 2, 71, and 75 has been deleted...
Topics
- Animals
- Cell Line
- Gene Deletion
- Genes, Reporter
- Genes, Viral
- Herpesvirus 1, Equid
- Horses
- Lac Operon
- Mutation
- Open Reading Frames
- Virus Cultivation
- Virus Replication
