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Article

Contribution of gene products encoded within the unique short segment of equine herpesvirus 1 to virulence in a murine model.

Virus research - 1 Dec 2002

Frampton Arthur R, Smith Patrick M, Zhang Yunfei, Matsumura Tomio, Osterrieder Nikolaus, O'Callaghan Dennis J

Abstract excerpt

The pathogenesis of three equine herpesvirus 1 (EHV-1) recombinants was assessed in a CBA mouse model. Sequences encoding the majority of glycoproteins I (gI) and E (gE) were deleted from the pathogenic EHV-1 strain RacL11 (L11deltagIdeltagE), and sequences comprising the 3859 bp deletion within the strain KyA U(S) segment, which includes genes 73 (gI), 74 (gE), and 75 (putative 10 kDa protein 75), were...

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PMID: 12457983
DOI: 10.1016/s0168-1702(02)00245-9

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MIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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