Article
Equine herpesvirus type 1 ORF51 encoding UL11 as an essential gene for replication in cultured cells.
Archives of virology - 1 Mar 2018
Badr Yassien, Okada Ayaka, Abo-Sakaya Rania, Beshir Emad, Ohya Kenji, Fukushi Hideto
Abstract excerpt
Equine herpesvirus type 1 (EHV-1) UL11 is a 74-amino-acid tegument protein encoded by ORF51 of the EHV-1 genome. EHV-1 UL11 was previously reported by other researchers using the RacL22 and RacH strains to be nonessential for viral replication in cultured cells. Here, we constructed UL11 mutant viruses including a UL11 null mutant and three C-terminal truncated mutants, for further characterization of EHV-1 UL11...
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