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Article

Evaluation of running conditions for SSCP analysis: application of SSCP for detection of point mutations in the LDL receptor gene.

PCR methods and applications - 1 Dec 1993

Leren T P, Solberg K, Rødningen O K, Ose L, Tonstad S, Berg K

Abstract excerpt

We have performed analyses of single-strand conformation polymorphisms (SSCP) of the promoter region and the translated parts of the 18 exons of the low-density lipoprotein receptor (LDLR) gene. DNA from 20 unrelated familial hypercholesterolemia (FH) patients was studied. Four different running...

Topics

Base Sequence
DNA Primers
Electrophoresis, Polyacrylamide Gel
Genotype
Humans
Molecular Sequence Data
Pilot Projects
Point Mutation
Polymorphism, Genetic
Receptors, LDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8118396
DOI: 10.1101/gr.3.3.159

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8118396-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Evaluation of running conditions for SSCP analysis: application of SSCP for detection of point mutations in the LDL receptor gene.PMID 8118396Read ↗

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