Article
Prenatal diagnosis of an extranumerary i(22p) with normal phenotype.
Annales de genetique - 1 Jan 1993
Doneda L, Dalprà L, Tibiletti M G, Larizza L
Abstract excerpt
A DA-Dapi and AgNOR-negative extranumerary chromosome was identified prenatally in a male fetus and also found in his normal father. Fluorescence in situ hybridization using repetitive DNA probes showed that the minute marker was positive at both ends for beta-satellite sequences, while its centromere was recognized by a 22 alphoid probe. It is concluded that the non-mosaic familial marker represents a 22p...
Topics
- Adult
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 22
- Family
- Female
- Humans
- In Situ Hybridization, Fluorescence
- Karyotyping
- Male
- Metaphase
- Middle Aged