Article
A rare 6q11+ heteromorphism: cytogenetic analysis and in situ hybridization.
Human heredity - 1 Jan 2000
Lin M S, Zhang A, Fujimoto A, Wilson M G
Abstract excerpt
A rare variant of 6q11+ heteromorphism was found in a fetus and the mother during amniocentesis. The G- and Q-banding and DA/DAPI stain were negative. The C-banding was positive and the C-banded segment was 3-fold longer in the variant than in its homologue. Neither of the C-banded regions of chromosomes 6 decondensed when exposed to distamycin A or 5-azacytidine. A DNA replication study indicated that the...
Topics
- Amniocentesis
- Chromosome Banding
- Chromosomes, Human, Pair 6
- Female
- Genetic Variation
- Humans
- In Situ Hybridization
- Karyotyping
- Pregnancy