Article
Predisposing genes in breast and ovarian cancer: an overview.
Tumori - 31 Oct 1993
Smith S A, Ponder B A
Abstract excerpt
The isolation of genes that predispose to familial disease is an important goal in cancer research. The identification of such genes "opens up" the possibility of genetic diagnosis in families so that individuals who are at risk of cancer through inheriting a predisposing mutation can be identified. Genes that are involved in familial cancer syndromes may also be important in the pathogenesis of sporadic forms of...
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