Article
The Role of Hereditary Factors in Ovarian Carcinoma.
Clinical obstetrics and gynecology - 1 Dec 2017
Schrader Kasmintan A
Abstract excerpt
Cancer is a disease of the genome, in which mutations in particular genes and pathways give rise to tissue-specific genotype-phenotype correlations. In tumors associated with hereditary cancer syndromes, a person is generally born with the first mutation relevant to the development of their cancer. In this chapter we will discuss the genes that have been associated with germline mutations that confer a moderate...
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