Evidence of a genetic marker associated with early onset in Friedreich's ataxia.

doi:10.1007/BF00818715

Article

Evidence of a genetic marker associated with early onset in Friedreich's ataxia.

Journal of neurology - 1 Jan 1993

Cocozza S, Antonelli A, Campanella G, Cavalcanti F, De Michele G, Di Donato S, Filla A, Monticelli A, Pianese L, Piccinelli A

Abstract excerpt

We evaluated the association between age at onset of Friedreich's ataxia and alleles of two restriction fragment length polymorphisms (RFLP) at D9S15 and D9S5 in the 9q13-9q21.1 region. We studied 65 Italian patients from 49 families. Age at onset was not normally distributed in our patients, sug...

Topics

Adolescent
Adult
Age Factors
Alleles
Child
Child, Preschool
Friedreich Ataxia
Genetic Markers
Genotype
Humans
Polymorphism, Genetic

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