Friedreich's disease. A linkage study in southern and central Italy.

Article

Friedreich's disease. A linkage study in southern and central Italy.

Acta neurologica - 1 Jan 2000

Cavalcanti F, Cocozza S, Filla A, De Michele G, Pianese L, Porcellini A, Monticelli A, Pandolfo M, Banfi S, Varrone S

Abstract excerpt

We studied linkage and linkage disequilibrium between the genetic locus of Friedreich's disease (FRDA) and two maker loci (D9S15 and D9S5) of chromosome 9q13-q21.1 in 49 subjects from 12 families in southern and central Italy. No recombination event occurred between D9S15 and D9S5, or between the...

Topics

Alleles
Chromosomes, Human, Pair 9
Friedreich Ataxia
Gene Frequency
Genetic Markers
Haplotypes
Humans
Italy
Linkage Disequilibrium
Lod Score
Polymorphism, Restriction Fragment Length

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