Article
Familial clustering and genetic background of primary biliary cirrhosis in Japan.
Digestive diseases and sciences - 1 Sept 2010
Yanagisawa Masatoshi, Takagi Hitoshi, Takahashi Hitomi, Uehara Masahiro, Otsuka Toshiyuki, Yuasa Kazuhisa, Hosonuma Kenichi, Mori Masatomo
Abstract excerpt
BACKGROUND: Primary biliary cirrhosis (PBC) is regarded as an autoimmune liver disease and familial clustering of PBC could represent some genetic predisposition to the disease. AIMS: To elucidate the genetic background of PBC by investigating familial cases of PBC. METHODS: Familial cases were picked out from 171 PBC patients who enrolled in this study. We analyzed them and their family members, and compared...
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