Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unusual organization of the human T-cell receptor beta-chain gene complex is linked to recombination hotspots.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1993

Seboun E, Houghton L, Hatem C J, Lincoln R, Hauser S L

Abstract excerpt

Two rare Sfi I polymorphisms of 360 kb and 280 kb present within the human T-cell antigen receptor beta-chain gene complex were revealed by pulsed-field gel electrophoresis. They represent allelic variants of the polymorphic 330- and 300-kb Sfi I fragments previously described. The 360-kb polymorphism results from duplication of the 30-kb DNA fragment responsible for the 330/300-kb insertion/deletion-related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Multigene Family

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Share to Recombination, Genetic

Share to Sequence Deletion

Source

Open in PubMed Open full text

Identifiers

PMID: 8099448
DOI: 10.1073/pnas.90.11.5026
PMCID: PMC46646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Unusual organization of the human T-cell receptor beta-chain gene complex is linked to recombination hotspots.PMID 8099448Read ↗

The complete 685-kilobase DNA sequence of the human beta T cell receptor locus.Semantic proximity Read ↗

Characterization of the patterns of polymorphism in a "cryptic repeat" reveals a novel type of hypervariable sequence.Semantic proximity Read ↗

Origins of polymorphism at a polypurine hypervariable locus.Semantic proximity Read ↗

Characterization of hypervariable locus-specific probes derived from a (CAC)5/(GTG)5 multilocus fingerprint in various Eurasian populations.Semantic proximity Read ↗

AvaI polymorphism in the human transferrin gene.Semantic proximity Read ↗

A new MspIPCR-RFLP in the human LDL receptor gene.Semantic proximity Read ↗

Sequence analysis of cloned human satellite DNAs reveals nonrandom variations.Semantic proximity Read ↗

Frequency and polymorphism of simple sequence repeats in a contiguous 685-kb DNA sequence containing the human T-cell receptor beta-chain gene complex.Semantic proximity Read ↗

The human low affinity immunoglobulin G Fc receptor IIC gene is a result of an unequal crossover event.Semantic proximity Read ↗

Prevalence and polymorphism of human VH3 genes.Semantic proximity Read ↗

TSPY variants in six loci on the human Y chromosome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.