Localization of the hydroxyindole-O-methyltransferase gene to the pseudoautosomal region: implications for mapping of psychiatric disorders.

doi:10.1093/hmg/2.2.127

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Article

Localization of the hydroxyindole-O-methyltransferase gene to the pseudoautosomal region: implications for mapping of psychiatric disorders.

Human molecular genetics - 1 Feb 1993

Yi H, Donohue S J, Klein D C, McBride O W

Abstract excerpt

The human hydroxyindole-O-methyltransferase (HIOMT) gene has been mapped to the X chromosome using cDNA probes from the 3' and 5' regions of a human cDNA clone. Southern blot analysis of a panel of human-rodent somatic cell hybrid DNAs revealed that the gene was localized to the short arm of chro...

Topics

Acetylserotonin O-Methyltransferase
Alleles
Animals
Base Sequence
Chromosome Mapping
DNA
Genetic Linkage
Humans
Hybrid Cells
Mental Disorders
Mice
Molecular Sequence Data
Pedigree
Polymorphism, Restriction Fragment Length
X Chromosome

Source

Open in PubMed

Identifiers

PMID: 8098975
DOI: 10.1093/hmg/2.2.127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8098975-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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