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Article

An examination of linkage of schizophrenia and schizoaffective disorder to the pseudoautosomal region (Xp22.3)

The British journal of psychiatry : the journal of mental science - 1 Feb 1994

Crow T J, Delisi L E, Lofthouse R, Poulter M, Lehner T, Bass N, Shah T, Walsh C, Boccio-Smith A, Shields G

Abstract excerpt

We investigated linkage between schizophrenia and the loci DXYS14, DXYS17, and MIC2 within the pseudoautosomal region in 85 families with two or more siblings suffering from schizophrenia or schizoaffective disorder. A maximum lod score of 2.44 was reached at MIC2, with a dominant model of inheritance at a recombination fraction of 0.367 in females and 0.046 in males (a F:M sex ratio > 1, i.e. opposite to that...

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PMID: 7818635
DOI: 10.1192/bjp.164.2.159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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An examination of linkage of schizophrenia and schizoaffective disorder to the pseudoautosomal region (Xp22.3)PMID 7818635Read ↗

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Pseudoautosomal locus for schizophrenia excluded in 12 pedigrees.Semantic proximity Read ↗

Evidence for a pseudo-autosomal locus for schizophrenia using the method of affected sibling pairs.Semantic proximity Read ↗

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Failure to establish linkage on the X chromosome in 301 families with schizophrenia or schizoaffective disorder.Semantic proximity Read ↗

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Schizophrenia susceptibility gene locus at Xp22.3.Semantic proximity Read ↗

A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes.Semantic proximity Read ↗

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