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Article

Oxidation, cross-linking, and insolubilization of recombinant tropoelastin by purified lysyl oxidase

1 May 1993

Abstract excerpt

The use of recombinant human tropoelastin (rTE) and selected variants thereof as substrates for the assay of lysyl oxidase activity in vitro was explored. The possibility was also assessed that an insoluble elastin-like product could be generated from this elastin precursor in the absence of other macromolecules found associated with elastin in vivo. rTE was more efficiently oxidized by lysyl oxidase than the...

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PMID: 8098038
DOI: 10.1016/s0021-9258(18)82207-4

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