[Molecular biological analysis of HLA class II gene in autoimmune hepatitis among Japanese].

Abstract excerpt

The frequencies of HLA B54, DR4, DR53 and DQ4 were significantly higher in patients with autoimmune hepatitis than in healthy controls. HLA-DR4 was most frequently associated with autoimmune hepatitis. To define the HLA class II gene which has the susceptibility or resistance to autoimmune hepatitis, we performed HLA class II genotyping using polymerase chain reaction-restriction fragment length polymorphisms...

Topics

• Asian People
• Autoimmune Diseases
• Genes, MHC Class II
• Genotype
• Hepatitis
• Humans
• Japan