Article
[The molecular basis of HLA DR4 alleles associated with rheumatoid arthritis in a Chinese population].
Zhonghua yi xue za zhi - 1 Jul 1994
Zhu N S, Wang Y X, Wang F Q
Abstract excerpt
HLA-DR4 gene was studied by polymerase chain reaction method in 95 patients with rheumatoid arthritis(RA) and 130 normal controls in a Shanghai population. The results showed that the DR4 was significantly associated with RA(RR = 3.1, chi 2 = 13.8, P < 0.005). The second exon of DR4 gene was also...
Topics
- Alleles
- Arthritis, Rheumatoid
- Asian People
- Base Sequence
- DNA
- Disease Susceptibility
- Genes, MHC Class II
- HLA-DR4 Antigen
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction