Article
The genetic basis of responses to drugs--a rheumatological perspective.
British journal of rheumatology - 1 Mar 1993
Waring R H, Emery P
Abstract excerpt
The wide individual variations seen in all metabolic pathways which have been examined largely explain differences in drug dose response and toxicity. In some cases, distinct sub-sets occur where the enzyme activity is markedly different from that in the rest of the population (genetic polymorphi...
Topics
- Anti-Inflammatory Agents
- Genotype
- Humans
- Phenotype
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Rheumatic Diseases
