Article
The legacy of pharmacogenetics and potential applications.
Mutation research - 8 Aug 2001
Weber W W
Abstract excerpt
Some 40 years of pharmacogenetic research indicates that knowledge of human genetic diversity is essential to a broader understanding of variation in human drug response, and suggests that drug therapy tailored to the genetic characteristics of the individual may be a realistic goal. Aided by new technologies, molecular studies of genetic polymorphisms of many human enzymes, receptors, and other proteins indicate...
Topics
- Animals
- Drug Design
- Genetic Variation
- History, 20th Century
- Humans
- Pharmacology
- Polymorphism, Genetic