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Article

Dual mode cytotoxicities of reactive oxygens on L5178Y radiosensitive mutant M10.

Free radical biology & medicine - 1 Oct 1992

Ito A, Shinohara K

Abstract excerpt

Cytotoxic effects of O2- and H2O2 on mammalian cells were investigated in comparison with the relative sensitivity of mouse L5178Y cells and its radiosensitive mutant M10. Both O2- and H2O2 exhibited two different modes of cytotoxic actions depending on their exposure rates: At a high exposure rate (4.3 nmol of O2-/mL/min), M10 was more sensitive to O2- than L5178Y normal type cell, in agreement with the case of...

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Identifiers

PMID: 1327978
DOI: 10.1016/0891-5849(92)90177-i

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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