Article
Evidence for autosomal dominant inheritance and race-specific heterogeneity in early-onset periodontitis.
Journal of periodontology - 1 Jun 1994
Marazita M L, Burmeister J A, Gunsolley J C, Koertge T E, Lake K, Schenkein H A
Abstract excerpt
Early-onset periodontitis (EOP) refers to a group of severe periodontal diseases with age of onset near puberty that are characterized by rapid destruction of the tissues supporting the teeth in otherwise healthy individuals. Mixed model segregation analyses of 100 families, ascertained through 104 probands with EOP, were carried out to test major locus and multifactorial hypotheses for the etiology of EOP....
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