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Article

A major gene effect controls resistance to caries.

Journal of dental research - 1 Jun 2011

Werneck R I, Lázaro F P, Cobat A, Grant A V, Xavier M B, Abel L, Alcaïs A, Trevilatto P C, Mira M T

Abstract excerpt

Despite recent advances revealing genetic factors influencing caries susceptibility, questions regarding the model of inheritance involved are yet to be addressed. We conducted a Complex Segregation Analysis on decayed teeth in a sample of homogenous, isolated families recruited from the Brazilian Amazon. A dominant, major gene effect controlling resistance to phenotype was detected. The frequency of the...

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Identifiers

PMID: 21364090
DOI: 10.1177/0022034510397614
PMCID: PMC3318028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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