Article
PET112, a Saccharomyces cerevisiae nuclear gene required to maintain rho+ mitochondrial DNA.
Current genetics - 1 Apr 1994
Mulero J J, Rosenthal J K, Fox T D
Abstract excerpt
The nuclear gene PET112 was originally identified by a mutation (pet112-1) that specifically blocked accumulation of cytochrome c oxidase subunit II. The mutation causes a post-transcriptional defect since the level of COX2 mRNA in the mutant is the same as in the wild-type. However, PET112 does not have a function similar to that of PET111, a COX2 mRNA-specific translational activator: while pet111 mutations are...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cell Nucleus
- Chromosome Mapping
- Cloning, Molecular
- DNA, Mitochondrial
- Genes, Fungal
- Genome, Fungal
- Molecular Sequence Data
- Mutation