Article
Functional interactions among two yeast mitochondrial ribosomal proteins and an mRNA-specific translational activator.
Genetics - 1 Feb 1991
Haffter P, McMullin T W, Fox T D
Abstract excerpt
Expression of the Saccharomyces cerevisiae mitochondrial gene coding cytochrome c oxidase subunit III is specifically activated at the level of translation by at least three nuclear genes, PET122, PET494 and PET54. We have shown previously that carboxy-terminal deletions of PET122 are allele-specifically suppressed by mutations in an unlinked nuclear gene, termed PET123, that encodes a small subunit ribosomal...
Topics
- DNA, Mitochondrial
- Electron Transport Complex IV
- Genes, Fungal
- Genes, Suppressor
- Genotype
- Macromolecular Substances
- Mitochondria
- Models, Genetic
- Phenotype
- Protein Biosynthesis
- RNA, Messenger