Article
Embryonic kidney rudiments grown in adult mice fail to mimic the Wilms' phenotype, but show strain-specific morphogenesis.
Experimental nephrology - 1 Jan 2000
Armstrong J F, Kaufman M H, van Heyningen V, Bard J B
Abstract excerpt
12.5- to 14.5-day mouse embryonic kidney fragments were grown syngeneically under kidney or testis capsules in 3 mouse strains for 5-26 weeks to reproduce the Wilms' tumour (WT) phenotype previously reported. About 65% of the transplants grew, but none showed true WT morphology, invaded local tis...
Topics
- Animals
- Female
- Fetal Tissue Transplantation
- Gene Expression
- Genes, Wilms Tumor
- In Situ Hybridization
- Kidney Neoplasms
- Kidney Transplantation
- Male
- Mice
- Mice, Inbred CBA
- Phenotype
- Pregnancy
- Species Specificity
- Transplantation, Isogeneic
- Wilms Tumor