Article
Extreme evolutionary conservation of QM, a novel c-Jun associated transcription factor.
Human molecular genetics - 1 May 1994
Farmer A A, Loftus T M, Mills A A, Sato K Y, Neill J D, Tron T, Yang M, Trumpower B L, Stanbridge E J
Abstract excerpt
QM is a 214 amino acid polypeptide, encoded by a gene (DXS648) in Xq28, that contains a high percentage of charged amino acids and has been found to bind c-Jun and DNA. Searches of the GenBank database revealed no matches between QM and any other known transcription factors. However, we and others have isolated QM homologs from a diverse array of eukaryotes. Alignment of these sequences indicated a high degree of...
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