Article
Discoordinate regulation of contractile protein gene expression in the senescent rat myocardium.
Journal of molecular and cellular cardiology - 1 Apr 1994
Ball K L, Solaro R J
Abstract excerpt
The myocardium is a highly adaptive tissue, as evidenced by phenotypic alterations throughout development and under conditions of altered hemodynamic load. With pressure overload, the myocardium displays adult-to-fetal transitions in expression of contractile and non-contractile proteins. Most in...
Topics
- Adenosine Triphosphatases
- Aging
- Animals
- Blotting, Northern
- Blotting, Western
- Contractile Proteins
- DNA
- Electrophoresis, Polyacrylamide Gel
- Gene Expression Regulation
- Hemodynamics
- Male
- Myocardium
- Myosins
- Phenotype
- RNA, Messenger
- Rats
- Rats, Inbred F344
- Troponin